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University of Pennsylvania Clinical Research Nurse C (Neurology) in Philadelphia, Pennsylvania

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America’s Best Employers By State in 2021.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

COVID-19 vaccination is a requirement for all positions at the University of Pennsylvania. New hires are expected to be fully vaccinated before beginning work at the University. For more information about Penn’s vaccine requirements and the use of Penn Open Pass, visit the Penn COVID-19 Response website (https://coronavirus.upenn.edu/) for the latest information.

Posted Job Title

Clinical Research Nurse C (Neurology)

Job Profile Title

Clinical Research Nurse C

Job Description Summary

The NeuroGeneRx Center within the Department of Neurology is seeking a registered nurse with licensure and in good standing to practice in the Commonwealth of Pennsylvania to provide comprehensive professional nursing care in a clinical research environment. The Clinical Research Nurse C (CRN C) will be responsible for coordinating early phase clinical trials involving various sponsors and innovative nucleic acid-based therapies for Neurological diseases. This position functions as part of a multidisciplinary team and reports to the NeuroGeneRx Program Manager. This area of research requires dedicated attention and care to ensure subject safety and well-being. The successful candidate will comply with all policies relating to UPHS, JCAHO, ICH/GCP, FDA, HHS, and other regulatory standards.

Job Description

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Job Description

The NeuroGeneRx Center within the Department of Neurology is seeking a registered nurse with licensure and in good standing to practice in the Commonwealth of Pennsylvania to provide comprehensive professional nursing care in a clinical research environment. The Clinical Research Nurse C (CRN C) will be responsible for coordinating early phase clinical trials involving various sponsors and innovative nucleic acid-based therapies for Neurological diseases. This position functions as part of a multidisciplinary team and reports to the NeuroGeneRx Program Manager. This area of research requires dedicated attention and care to ensure subject safety and well-being. The successful candidate will comply with all policies relating to UPHS, JCAHO, ICH/GCP, FDA, HHS, and other regulatory standards.

Specific responsibilities include (but are not limited to):

  • Managing and coordinating some or all aspects of clinical trials throughout their entire lifecycle (start-up, protocol implementation, and closure). Providing input into the development of efficient work flows related to the studies.

  • Acting as a liaison to sponsors, patients and investigational teams. Developing and maintaining communication with the various clinical teams, including but not limited to pharmacy, radiology, neurosurgery, periop, advanced practitioners, neurology outpatient clinic and inpatient units, CHPS outpatient and inpatient nursing units, and laboratory. Providing in-service and support to clinical or CHPS staff, as appropriate. Providing ongoing service education updates to all investigators that have eligible participants for clinical research trials.

  • Preparing, collecting and submitting study regulatory documents to the sponsor and all applicable institutional committees (e.g. IRB, IBC, CTRC, CAMRIS, CACTIS, etc.) for initial approval, continuing reviews and for approval of any amendments.

  • Caring for subjects of all age groups from young adult through geriatrics in accordance with protocol requirements as well as clinical and research guidelines. Handling any questions subjects may have regarding protocol specifics, investigational products, lab results, effects of therapies, medications, and symptom management within level of expertise and referring other questions to the PI or medical team in order to obtain guidance or assistance.

  • Providing oversight and/or completing study evaluations, data collection, assessments, source documents and case report forms. Performing necessary screening and routine evaluations in clinical trials including phlebotomy, physical assessments, photography, EKGs, or others as indicated within required time frames and with attention to detail according to the protocol. Coordination will also include placing/releasing EPIC orders, administering or providing therapeutic agents and/or study interventions, as appropriate, documenting administration in EPIC, and transporting, processing and/or shipping biological samples.

  • Demonstrating vigilance in patient safety and protocol compliance. Reviewing all clinical and laboratory data and adverse events, reporting in real-time to the PI for assessment and review, and communicating with medical staff regarding protocol-specific management of toxicities and adverse events.

  • Participating in the conduct of audits by study sponsors, CROs, the FDA, the University of Pennsylvania, and other groups.

  • Participating in core study team and ongoing protocol training/compliance meetings. Participating in working groups within the research team that will maximize the efficiency and quality of research performed, including developing SOPs.

  • Providing coverage and support to other research nurses and coordinators to meet center staffing needs. Acting as a mentor to newly hired nurses, coordinators and research assistant.

  • Maintaining competency professionally and personally. Completing all necessary protocol specific trainings as well as required organizational trainings (Penn CRC, ACLS, CPR, PA RN licensure) and others as directed by the NeuroGeneRx Center or study-specific requirements.

  • Other responsibilities delegated as needed.

The CRN C will promote institutional values of patient and visitor satisfaction by demonstrating courtesy and respect for patients and their families, visitors and other employees. The CRN C will demonstrate competence in the assessment, treatment and care of patients, and is expected to exhibit a professional and compassionate demeanor in performance of responsibilities and to be unfailingly responsive to the needs of patients.

Work requires 40 hours per week, with on-site presence and interaction with research subjects and teams. Variable hours of duty on week days may be necessary to accommodate study protocol requirements. Some work-related responsibilities may occur outside of usual hours, and conference-related travel may be required.

The position is contingent on continued funding.

Qualifications

REQUIRED: Bachelor’s degree required and 2-4 years of related experience (or equivalent combination of education and experience). Registered Nurse; licensure in Commonwealth of PA without restriction or limitation.

PREFERRED: Specialty neuroscience nursing certification (CNRN) is preferred. Prior experience with industry-sponsored trials, early phase trials, gene and molecular therapies, regulatory/ethics reviews, phlebotomy and/or injection is preferred. The CRN C should be highly motivated and detail-oriented, have strong planning, organizational, multi-tasking, and prioritizing capabilities, and be capable of solving problems as they arise, but willing to seek help as appropriate to complete the work accurately and efficiently. The CRN C should have a strong ability to communicate with clinicians, researchers, sponsors, patients and families.

Cover letter and resume are required.

Working ConditionsOffice, Library, Computer RoomPhysical EffortTypically sitting at a desk or table; Occasional lifting 25 lb. or less

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$50,684.00 - $91,232.00

Affirmative Action Statement Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

University Benefits

  • Health, Life, and Flexible Spending Accounts : Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family’s health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.

  • Tuition : Take advantage of Penn's exceptional tuition benefits . You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.

  • Retirement: Penn offers generous retirement plans to help you save for your future. Penn’s Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.

  • Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family—whatever your personal needs may be.

  • Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you’re newly hired, you won’t have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.

  • Wellness and Work-life Resources : Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That’s why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.

  • Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.

  • University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University’s libraries and athletic facilities, or visit our arboretum and art galleries. There’s always something going on at Penn, whether it’s a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you’re right in the middle of the excitement—and you and your family can enjoy many of these activities for free.

  • Discounts and Special Services : From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.

  • Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.

  • Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.

  • Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.

    To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay

    The University of Pennsylvania's special character is reflected in the diversity of the Penn community. We seek talented faculty and staff who will constitute a vibrant community that draws on the strength that comes with a substantive institutional commitment to diversity along dimensions of race, ethnicity, gender, sexual orientation, age, religion, disability, veteran status, interests, perspectives, and socioeconomic status. Grounded in equal opportunity, nondiscrimination, and affirmative action, Penn's robust commitment to diversity is fundamental to the University's mission of advancing knowledge, educating leaders for all sectors of society, and public service. The University of Pennsylvania prohibits unlawful discrimination based on race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

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